This has formed major implications for how we can treat heart disease which is the main cause of death in the western world due to bad dieting, smoking & a lack of exercise. This method is achieve by injecting a lipid-incased substance into a patient. Once inside the body, the substance stimulates cell growth of new blood vessels from pre-existing ones, including those lost from a heart disease. It has been tested successfully on rats and the studies were published in the Proceedings of the National Academy of Sciences.
The method was developed Aaron Baker who is an assistant professor in the Department of Biomedical Engineering. He said
“Our method basically delivers extra components that can restore growth factor responsiveness to the tissue of patients with long-standing clinical disease.”
The following video shows the blood vessels growing (speeded up).
The new treatment can be proven crucial to save lives. Chronic myocardial ischemia disease affects up to 27 million patients in the United States alone. The disease reduces blood flow in the heart and lower limbs,ultimately causing organ dysfunction and failure. However the new treatment is said to most probably be able to cure this disease though producing this treatment and then stocking it in the market may cost a lot. Therefore countries in the third world or in poverty will most likely have less access to this cure – another example of the harsh reality between the gap of the rich and the poor which only seems to be becoming wider. Doctors have treated ischemia by physically opening the closed artery with a stent or surgically rerouting blood flow to the damaged tissue. However this method has limitations as well as not being effective in the long-term.
In recent times, the challenge for scientists as well as chemical engineers has been to bind specific substances with cell receptors – the molecules found on the surface of the cell that receive chemical signals and control activities in the cell from outside sources. Baker’s method creates the growth factors in synthetic lipid-based nanoparticles. The nanoparticles contain receptors that, when delivered with the growth factor, improve cell binding so that the growth factor can direct the targeted cell to divide and form new cells. This results in blood vessel growth.
As years go by science seems to surprise with what seemed a miracle 10 years. Makes me wonder what science has for us in the years to come. Only time will tell.
In the modern-day it is quite common for people to who have been unlucky in love will be said to suffer from a “broken heart.” It turns out that a broken heart is an actual & real medical condition. Broken heart syndrome occurs during highly stressful or emotional times, such as a painful breakup, the death of a spouse, or the loss of a job.
The medical name for Broken Heart Syndrome is stress Cardiomyopathy. In extreme cases symptoms are similar to those of a heart attack, including chest pain and difficulty breathing. Only in extreme cases it’s difficult to distinguish between broken heart syndrome and a heart attack, so if you experience symptoms, don’t assume you’re having broken heart syndrome – call 999. However symptoms for Broken Heart Syndrome are reversible unlike a heart attack. Over time, the symptoms go away. And unlike heart attack patients, people with broken heart syndrome do not suffer lasting damage to their hearts.
The Causes of The Heartbroken Syndrome?
In the Hopkins study, to be published in The New England Journal of Medicine online Feb. 10, the research team found that some people may respond to sudden, emotional stress by releasing large amounts of catecholamines (adrenalin and noradrenaline) into the blood stream. These chemicals are temporarily toxic to the heart, stunning the muscle and producing symptoms similar to a typical heart attack. Cardiologist Dr. Binh An P. Phan has said
“Most people will get better in a few weeks without medical treatment. During an extremely stressful event, the heart can be overwhelmed with a surge of adrenalin and other stress hormones. This can cause a narrowing of the arteries that supply blood to the heart. It’s similar to what happens during a heart attack, when a blood clot in a coronary artery restricts blood supply to heart muscle”
While the folklore of “broken heart” syndrome has been around for decades. Many believed a broken heart has been a psychological condition however recent research has proven it is in fact a physical condition due to biological chemicals. Doctors expect the frequency of heart-broken syndrome to increase as more physicians learn to recognize the syndrome’s unique clinical features.
The researchers also plan to study whether certain patients have a specific genetic vulnerability for developing stress cardiomyopathy (broken heart syndrome). It is suggested the best way to reverse the effects of cardiomyopathy is by exercise and keeping the body fit as well as a healthy diet as it will release hormones in the brain that in a sense “up-lift” your emotions. These hormones can also be triggered to be released, in more concentrated and effective forms, by the affection of a partner. As Valentines day approaches, it is your perfect chance to reverse the effects of Cardiomyopathy and to fix a broken heart. 🙂